There are numerous studies on endometrial cancer. The results suggest an inverse relationship between physical activity and the incidence of endometrial cancer. These studies suggest that women who are physically active have a 20 percent to 40 percent lower risk of endometrial cancer, with the greatest reduction in risk among those with the highest levels of physical activity. Risk does not appear to vary with age.
Changes in body mass and changes in the levels and metabolism of sex hormones, such as estrogen, are primarily intended to explain the association between physical activity and endometrial cancer biological mechanisms. However, less than half of the studies in this area have also been adjusted for the potential use of hormones after menopause effect, which can increase the risk of endometrial cancer. A few studies have examined whether the effect of physical activity varies with the weight of women.
Source: National Cancer Institute
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